TO FIND OUT THE PREVALENCE OF LEPTOSPIRAL INFECTION IN PATIENTS OF PYREXIA OF UNKNOWN ORIGIN, JAUNDICE, BY IMMUNOLOGICAL AND MOLECULAR TECHNIQUES AND THEIR COMPARISON – A PROSPECTIVE STUDY.

Dr Arun Jain, Dr Bharat Jain

Abstract


Introduction :- Leptospirosis is caused by infection with pathogenic spirochaetes of the genus Leptospira. It could be diagnosed with the help of Dark ground microscopy, in- vitro culture, serology and molecular method, each one with its merits and de- merits.

Aims & Objectives :- To find out the prevalence of leptospiral infection in patients of pyrexia of unknown origin, jaundice, by immunological and molecular techniques

Materials & Method:- In this study 110 urban – rural patients with history of pyrexia of unknown origin or jaundice were selected.

Conclusion:- In serological tests IgM positivity was found in 7 cases in pyrexia with jaundice group. Leptospira serovar autumnalis was found to be the most common that is 13 case, followed by serovar canicola 3 cases and icterohaemorrhagiae in 1 case.

Keywords


Leptospirosis, zoonosis, pathogenic

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